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Antibiotic and Antimicrobial Use in Dental Practice

Table of Contents:

Quick Cross-Reference Guide

Section 1 General Principles
1. Principles of Antimicrobial Chemotherapy in Dental and Orofacial Infections/Arie J. van Winkelhoff, Christina M. J. E. Vandenbroucke-Grauls
2. Microbiological Sampling and Sensitivity Testing/Arie J. van Winkelhoff, Christina M. J. E. Vandenbroucke-Grauls

Section 2 Drugs of Choice
3. Individual Drugs/Mariano Sanz, David Herrera
4. Topical Antimicrobial Agents: General Principles and Individual Drugs/Andrea Mombelli, Maurizio S. Tonetti
5. Topical and Systemic Antifungal and Antiviral Agents/Jacob Fleischmann

Section 3 Adverse Reactions
6. Allergic and Other Sensitivity Reactions/Larry J. Peterson
7. Adverse Microbiological Effects/Mariano Sanz, David Herrera

Section 4 Clinical Application
8. Antibiotics in Periodontal Therapy/Sebastian G. Ciancio, Arie J. van Winkelhoff
9. Oral Malodor/Sushma Nachnani
10. Antibiotics in Endodontic Therapy/J. Craig Baumgartner
11. Antibiotics for Oral and Maxillofacial Infections/Larry J. Peterson
12. Pediatric Considerations/Robert Lindemann, Douglas Harrington
13. Chemotherapeutic Agents in Restorative Dentistry/Perry R. Klokkevold
14. Antimicrobials in Implant Dentistry/Thomas Beikler, Thomas F. Flemmig

Section 5 Special Considerations
15. Prophylactic Antibiotic Use/Joan Otomo-Corgel, Stephen T. Sonis
16. Antimicrobial Therapy for Immunocompromised Patients/Joan Otomo-Corgel
17. Considerations for Female Patients/Joan Otomo-Corgel
18. Patients with Common Systemic Diseases/Mark J. Redd, Stefan A. Hienz
19. Legal Considerations/Edwin J. Zinman

Appendixes

Contributors

J. Craig Baumgartner, DDS, MS, PhD, Chairman, Department of Endodontology, Oregon Health Sciences University, Portland, Oregon
Thomas Beikler, Dr med, Assistant Professor, Clinic of Periodontology, Center for Dentistry and Oral Medicine, Westfalian-Wilhelms University, Muenster, Germany
Sebastian G. Ciancio, DDS, Professor and Chair, Department of Periodontics, Director, Center for Dental Studies, School of Dental Medicine, State University of New York, Buffalo, New York
Jacob Fleischmann, MD, Professor, Section of Oral Biology and Medicine, School of Dentistry, University of California at Los Angeles, Los Angeles, California
Thomas F. Flemmig, Prof Dr med dent, Chairman, Clinic of Periodontology, Center for Dentistry and Oral Medicine, Westfalian-Wilhelms University, Muenster, Germany
Larry Peterson, DDS, MS, Clinical Professor, Department of Oral and Maxillofacial Surgery, Ohio State University, Columbus, Ohio
Douglas Harrington, DDS, Private Practice, Pediatric Dentistry and Orthodontics, San Diego, California
David Herrera, DDS, Dr Odont, Associate Professor, Faculty of Odontology, Complutense University of Madrid, Madrid, Spain
Stefan A. Hienz, PhD, DMD, Section of Periodontics, School of Dentistry, University of California at Los Angeles, Los Angeles, California
Perry R. Klokkevold, DDS, MS, Associate Professor and Clinical Director, Postgraduate Periodontics and Implant Surgery, School of Dentistry, University of California at Los Angeles, Los Angeles, California
Robert Lindemann, DDS, MEd, MS, Professor and Associate Dean, School of Dentistry, University of California at Los Angeles, Los Angeles, California
Andrea Mombelli, DDS, PhD, Professor and Chair, Department of Periodontology and Oral Pathophysiology, School of Dental Medicine, University of Geneva, Geneva, Switzerland
Sushma Nachnani, MS, Director, University Health Resources Group, Culver City, California
Joan Otomo-Corgel, DDS, MPH, Chair of Research, Dental Service, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, California; Adjunct Assistant Professor, Section of Periodontics, School of Dentistry, University of California at Los Angeles, Los Angeles, California
Mark Redd, DDS, Private Practice, Periodontics and Dental Implants, Laguna Hill, California
Mariano Sanz, MD, DDS, Vice-Dean, Faculty of Odontology, Complutense University of Madrid, Madrid, Spain
Stephen T. Sonis, DMD, DMSc, Professor and Chair, Department of Oral Medicine and Diagnostic Sciences, Harvard School of Dental Medicine, Boston, Massachusetts; Chief, Division of Oral Medicine, Oral and Maxillofacial Surgery and Dentistry, Dana-Farber Cancer Institute, Boston, Massachusetts; Senior Surgeon, Brigham and Women’s Hospital, Boston, Massachusetts
Maurizio S. Tonetti, DMD, PhD, MMSc, Professor and Chair, Department of Periodontology, Eastman Dental Institute and Hospital, University College London, London, United Kingdom
Christina M.J.E. Vandenbroucke-Grauls, MD, PhD, Professor, Medical Microbiology and Infection Prevention, Academic Hospital Vrije University Amsterdam, Amsterdam, The Netherlands
Arie J. van Winkelhoff, PhD, Professor, Department of Oral Microbiology, Academic Centre for Dentistry Amsterdam, Amsterdam, The Netherlands
Edwin J. Zinman, DDS, JD, Attorney at Law, San Francisco, California; Former Lecturer, Department of Periodontology, University of California at San Francisco, San Francisco, California

Preface

Antibiotics and antimicrobials have become a critical and integral part of dental practice. Accordingly, there is a growing need for precise strategies and guidelines governing their use. The new and updated information contained in this completely revised second edition is essential for every practitioner. Although modernized in appearance and updated in content, the book remains the same important reference and resource that has become one of the most popular books in its field.

This second edition of Antibiotic and Antimicrobial Use in Dental Practice integrates basic facts and principles with concepts that have emerged during the last 6 years. As in the previous edition, a group of internationally recognized experts has been assembled to provide the most direct and pertinent information for application to clinical practice.

Above all, this book is user-friendly. Useful and informative tables, charts, algorithms, and information boxes support concise discussions of relevant information. In addition, icons have been generously dispersed throughout each chapter to alert the reader to important facts and principles.

A new chapter on general principles describes the infections and bacteriologically associated complications that can arise in the oral cavity. These conditions, diseases, and complications are among the most common situations dealt with in clinical practice. This background serves as the foundation for many of the systemic and topical agents described in the rest of the book.
Completely new or expanded chapters on viral and fungal infections, oral malodor, systemic disease complications, and special considerations for female patients, as well as a revised chapter on topical agents, offer a comprehensive view of the proper prescription and use of the bewildering array of agents currently available. Essential information about new therapies, including a form of periodontal therapy involving devices that deliver local controlled release of antimicrobials in the periodontal pocket, are discussed in a straightforward, practical manner.

Recognizing the integral role implants play in dental practice, specific guidelines are provided to assist the practitioner in the use of antimicrobials for the treatment of peri-implant infections as well as in the maintenance and treatment of plaque-associated conditions. Another chapter addresses the growing need for awareness of legal issues associated with the use of antibiotics and antimicrobials in clinical practice. This chapter illustrates the pertinent medicolegal and ethical issues through real-life examples drawn from cases, trials, and verdicts.

The chapter on restorative dentistry considerations discusses the mutual relationship between restorative dentistry and periodontics. This chapter also provides up-to-date information and suggestions for diagnosing, treating, and preventing infections in patients with removable prostheses.

Finally, this new edition consolidates the most significant information discussed in detail in the text in a series of highly useful quick-access tables, boxes, and charts. A listing of the most useful tables, boxes, and charts and where they can be found is provided in the Quick Cross-Reference Guide starting on page xiii.

The editors would like to thank the contributors for their excellent work and their dedication to improving the lives of patients, who depend on clinicians to have the most useful and accurate information possible. They also would like to thank the staff at Quintessence Publishing, whose collaboration and hard work helped to make this edition a truly comprehensive revision.

REVIEWS
".....Each chapter in the book is concise and the authors cite ample references. The book makes excellent use of the remarkably superb and informative tables, charts, algorithms and information boxes. Important areas are highlighted and icons are dispersed throughout the book to alert the reader to important facts and principles. The information boxes support concise discussions of relevant information.
The book starts with a 'quick cross-reference guide' which lists the pages in the book where information on a given topic has been summarized for easy access. This is a handy item when one needs to use the book as a quick reference to treat a certain condition with antibiotic therapy. It is a well-written and user-friendly text. I plan to use it as a reference book. The general dentist as well as the specialist will find this book beneficial."
Reviewed by Louis A. Imburgia, DDS, in CDS Review, September 2001