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Pharmacology and Therapeutics for Dentistry

New to this Edition

• A new chapter, Introduction to Antinociceptive Drugs, discusses the important topic of pain and provides new information on mechanisms of pain and therapeutic approaches to pain. • A new chapter on serotonin pharmacology and antimigraine drugs covers the roles of serotonin and the importance of agonist and antagonists at the many serotonin receptors. • A new chapter on Alternative Medicine in Dentistry provides a current treatment of chemicals used as alternative medicines and an assessment of the potential benefits and risks of a large number of these compounds. • New information on pharmacogenetics provides the latest findings on how an individual’s genetic traits affect his or her responses to drugs. • The scope of the Non-Opioid Analgesics chapter has been expanded to include non-opioid analgesics, nonsterioidal anti-inflammatory drugs, antirheumatic, and antigout drugs. • An expanded discussion of the endocrine system provides the most comprehensive coverage on the subject. • Discussions of drugs have been updated to include the latest drugs and their pharmacology. • Dental aspects of many drug classes have been expanded to include antibiotics, analgesics, and anesthetics. • The uses and mechanisms of action of drugs have been linked to the latest information on drug receptors. • Drug lists have been updated throughout the text to provide the most current information. • Website addresses have been added where appropriate to provide another avenue of drug information. • New figures help clarify mechanisms of drug action, in such areas as gastrointestinal drugs, cardiovascular drugs, and endocrine drugs. • For the first time, every book includes a free six-month subscription to Mosby's Drug Consult. Mosby's Drug Consult provides the most current, unbiased, accurate, and reliable drug information available!

Table of Contents

PART 1: PRINCIPLES OF PHARMACOLOGY 1. Pharmacodynamics: mechanisms of drug action 2. Pharmacokinetics: the absorption, distribution, and fate of drugs 3. Pharmacotherapeutics: the clinical use of drugs 4. Pharmacogenetics and general mechanisms of drug interactions PART II: PHARMACOLOGY OF SPECIFIC DRUG GROUPS 5. Introduction to autonomic nervous system drugs 6. Adrenergic agonists 7. Adrenergic blocking drugs 8. Cholinergic drugs 9. Antimuscarinic drugs 10. Drugs affecting nicotinic receptors 11. Introduction to central nervous system drugs 12. Psychopharmacology: antipsychotic and antidepressant drugs 13. Sedative-hypnotics, antianxiety drugs, and centrally acting muscle relaxants 14. Anticonvulsants 15. Antiparkinson drugs 16. Local anesthetics 17. Principles of general anesthesia 18. Agents used in general anesthesia, deep sedation, and conscious sedation 19. Introduction to antinociceptive drugs 20. Opioid analgesics and antagonists 21. Non-opioid analgesics; nonsterioidal anti-inflammatory drugs; and antirheumatic and antigout drugs 22. Histamine and histamine antagonists 23. Drugs affecting serotonin, antimigraine drugs, drugs for other pain syndromes 24. Antiarrhythmic drugs 25. Cardiac glycosides and other drugs used in heart failure 26. Antianginal drugs 27. Diuretic drugs 28. Antihypertensive drugs 29. Lipid-lowering drugs 30. Antianemic and hematopoietic stimulating drugs 31. Procoagulant, anticoagulant, and thrombolytic drugs 32. Drugs acting on the respiratory system 33. Drugs acting on the gastrointestinal tract 34. Pituitary, thyroid and parathyroid pharmacology 35. Adrenal corticosteroids 36. Insulin, oral hypoglycemics, and glucagons 37. Steroid hormones of reproduction and sexual development 38. Principles of antibiotic therapy 39. Antibacterial and antibiotic drugs 40. Antifungal and antiviral agents 41. Immunotherapy 42. Antineoplastic drugs 43. Aliphatic alcohols 44. Anticaries agents 45. Antiplaque/antigingivitis agents 46. Antiseptics and disinfectants PART III: SPECIAL SUBJECTS IN PHARMACOLOGY AND THERAPEUTICS 47. Analgesic use for effective pain control 48. Management of fear and anxiety 49. Antibiotic prophylaxis 50. Oral complications of cancer therapy 51. Drugs of abuse 52. Toxicology 53. Geriatric pharmacology 54. Drugs for medical emergencies 55. Prescription writing and drug regulations 56. Alternative medicine in dentistry Appendix I: Drug interactions in clinical dentistry Appendix II: Glossary of abbreviations

Author Information

By John A Yagiela, DDS, PhD; Frank J Dowd, DDS, Phd; and Enid A Neidle, PhD